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Targets Recommended: Others

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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T77359 Tezepelumab

Tezepelumab-ekko,MEDI 19929,AMG 157

Others Others
Tezepelumab (AMG 157) 是一种人源化靶向 TSLP 的单克隆抗体 (IgG2λ),阻止TSLP 与其异二聚体受体相互作用。Tezepelumab 可用于研究晚期哮喘疾病。

化合物

Tezepelumab
Cat.No: T77359
Synonym: Tezepelumab-ekko,MEDI 19929,AMG 157
Target: Others
Cat. No. Product Name Species Expression System
TMPK-01331 TSLPR Protein, Cynomolgus, Recombinant (His)

CRL2,CRLF2,IL-XR,CRLF2Y,p2RY8/CRLF2 fusion,TSLPR,

Cynomolgus HEK293 Cells
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
TMPJ-00530 TSLPR Protein, Mouse, Recombinant (hFc)

CRLF2,CRL2 cytokine receptor,TSLPR,CRL2,P2...

Mouse HEK293 Cells
TSLPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 62-88 KDa and the accession number is AAH23788.1.
TMPJ-00531 TSLPR Protein, Mouse, Recombinant (His)

Cytokine receptor-like 2,Thymic stromal-derived lym...

Mouse HEK293 Cells
TSLPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-40 KDa and the accession number is AAH23788.1.
TMPJ-00042 TSLP Protein, Human, Recombinant

TSLP,Thymic stromal lymphopoietin

Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral...

重组蛋白

TSLPR Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01331
Species: Cynomolgus
Expression System: HEK293 Cells
TSLPR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00530
Species: Mouse
Expression System: HEK293 Cells
TSLPR Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00531
Species: Mouse
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant
Cat.No: TMPJ-00042
Species: Human
Expression System: E. coli
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